Conditional inactivation ofTgfbr2in cranial neural crest causes cleft palate and calvaria defects
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چکیده
منابع مشابه
Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects.
Cleft palate and skull malformations represent some of the most frequent congenital birth defects in the human population. Previous studies have shown that TGFbeta signaling regulates the fate of the medial edge epithelium during palatal fusion and postnatal cranial suture closure during skull development. It is not understood, however, what the functional significance of TGFbeta signaling is i...
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ژورنال
عنوان ژورنال: Development
سال: 2003
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.00708